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Science (2011) 334:67883

however, it is important to realise that betacyanins are unlikely to be exclusively eliminated via the renal pathway [36] Indeed, the use of urinary excretion as a sole indicator of bioavailability has received criticism because it does not account for the biliary and circulatory clearance of compounds, thus underestimating true bioavailability [33]

The scientific studies of these experimental drugs were never large enough or long enough to establish a clear safety profile, so all we are left with are vague reassurances from tiny studies and testimonials from YouTubers and TikTokers

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