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Description

Microscopy and beta cell mass quantification The weight of the pancreas was determined at the time the mice were killed

All the variables are scaled relative to their values at day 1

Wedell-Neergaard, A

Constitutive overexpression of the proto-oncogenes c-myb in Balb/c-3T3 cells increases expression of both IGF-1 and IGF-1R, at least partly through an increased transcriptional activity and in this way abrogates the requirement for IGF-1 in the growing media (Kim et al, 1996)