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Arbutin inhibits tyrosinase activity competitively but at non-cytotoxic concentrations in a dose-dependent manner in cultured melanocytes

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The docket for this meeting, FDA-2025-N-6895, attracted approximately 1,860 public comments by the time it closed July 22

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Buse, MD, PhD, Distinguished Professor of Medicine, Director of the UNC Diabetes Care Center

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However, there are important challenges in the clinical application of endostatin related to the chemical nature of this protein

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