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They observed that the treatments increased superoxide dismutase activity but decreased peroxidase levels and had no effect on catalase

Preprocessing The gene expression microarray dataset was preprocessed using the R programming language, including gene name annotation, handling of missing values, and dealing with duplicate entries

In NRK-52E cells, TGF-1 stimulation considerably upregulated the expression levels of p53 and nuclear Nrf2 protein, which was consistent with the trend of erastin-induced cells and animal models, indicating that Nrf2 is probably related to ferroptosis under diabetic conditions[83]