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This creates a mechanistically coherent chain from butyrate depletion to mucosal oxygen dysregulation to barrier failure to dysbiosis expansion

3 Progress in Neurobiology

Recently, several studies have shown that lung cancer patients treated with antibiotics before immunotherapy have significantly worse responses to immunotherapy and survival (PFS and overall survival) than those who do not receive antibiotics, which might be related to the imbalance of gut microbiota caused by antibiotics (Pinato et al., 2019

These gene fragments were fused with corresponding trc promoter using overlap-extension PCR to form trc pro - ectA , trc pro - ectB , and trc pro - ectC