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Figure 3: Sample collection and handling protocol for accurate eicosanoid quantification LC-MS/MS Methods for Eicosanoid Profiling Eicosanoid quantification by LC-MS/MS presents analytical challenges distinct from routine lipidomics

However, in agreement with a causal role of moderately elevated circulating homocysteine levels in cardiovascular disease, some putative mechanisms have been identified that may explain the atherothrombogenicity of hyperhomo- cysteinemia