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Pancreatic islet dysfunction in type 2 diabetes: a rational target for incretin-based therapies

In this context, it is notable that although the specific activity of GGT in the whole adult rat liver is relatively low, the specific activity locally in the luminal membranes of the bile duct epithelium and bile canalicular membranes of hepatocytes is much higher (Tate and Meister, 1985)