mitochondrial glutathione depletion

mitochondrial glutathione depletion Ca2+-overloading by oxygen/glutathione depletion-boosted photodynamic therapy based on a CaCO3 nanoplatform for tumor synergistic therapy Age-related loss of mitochondrial glutathione

Name: mitochondrial glutathione depletion Ca2+-overloading by oxygen/glutathione depletion-boosted photodynamic therapy based on a CaCO3 nanoplatform for tumor synergistic therapy Age-related loss of mitochondrial glutathione
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Age related loss of mitochondrial glutathione exacerbates menadione induced inhibition of Complex I ScienceDirect Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation Mitochondrial Glutathione: Regulation and Functions Gaetano Calabrese, Bruce Morgan, Jan Riemer, 2017 Mitochondrial Glutathione: Recent Insights and Role in Disease

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Description

Iron can be stored in mitochondria and used for the synthesis of iron-sulfur (Fe-S) clusters and heme

Humans cannot synthesize folate and obtain it from natural sources of food, food fortified with folic acid (the synthetic fully oxidized monoglutamate form of folate), and through dietary supplements such as 5-methyltetrahydrofolate (5-MTHF) or 5-formyl tetrahydrofolic acid (folinic acid or leucovorin, an active form of folate)