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Connors, J

They are not substitutes for the underlying physiology

Chem Biol Interact 354:109821 Ochi T (1997) Arsenic compound-induced increases in glutathione levels in cultured Chinese hamster V79 cells and mechanisms associated with changes in -glutamylcysteine synthetase activity, cystine uptake and utilization of cysteine

These findings suggest isoform-selective HDAC inhibitors could provide more precise and safer therapeutic strategies compared with broad-spectrum HDAC blockade