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BCP-157

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Pentadecapeptide BPC 157 and the esophagocutaneous fistula healing therapy Vedran Cesarec Tomislav Becejac Marija Misic Zeljko Djakovic Danijela Olujic Domagoj Drmic Luka Brcic Dinko Stancic Rokotov Sven Seiwerth Predrag Sikiric ABSTRACT Esophagocutaneous fistulas are a failure of the NO-system, due to NO-synthase blockage by the NOS-blocker L-NAME consequently counteracted by l-arginine and gastric pentadecapeptide BPC 157 (l-arginine

WADA Prohibition The World Anti-Doping Agency classifies both peptides as prohibited substances for competitive athletes: Section S2 classification Peptide Hormones, Growth Factors, and Related Substances Prohibited at all times (both in-competition and out-of-competition) No Therapeutic Use Exemptions available not recognized as legitimate medical treatments Performance-enhancing potential acknowledged due to growth hormone secretagogue effects Detection methods under development for anti-doping testing programs WADAs position reflects that these peptides possess clear performance-enhancing properties and lack approved therapeutic applications that would justify medical use exemptions