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It activates genes involved in DNA repair, stress response, matrix remodeling and antioxidant defense, while suppressing genes associated with inflammation, fibrosis and tissue destruction

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According to USDA Agricultural Research Service data based on NHANES, approximately 6% of adults aged 60 and older in the United States are vitamin B12 deficient, defined as plasma B12 below 148 pmol/L (2009)

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10.3389/fphys.2018.00865 36 StrapazzonG.MalacridaS.VezzoliA.Dal CappelloT.FallaM.LochnerP.et al (2016)

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Exercise enhances these effects by increasing mitochondrial biogenesis and lipid oxidation and activating AMPK and PGC-1 (78)

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