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The majority of published research surrounding 5-Amino-1MQ centres on a single biological target: Nicotinamide N-methyltransferase (NNMT)

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When he came across the work of Werner Reichardt, Karl Gtz, and Martin Heisenberg* at the Max Planck Institute for Cybernetics, Tbingen, Wolf was fascinated by the idea of using engineering methods, combined with the use of brain mutants to understand the function of the relatively simple insect brain