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89 In contrast, some recent studies have found vitamin D status to have been unaffected by metformin use 62 and a placebo-controlled study found no effects of the drug at 4 or 16 months use in people with T2DM

Some other medications can lead to low levels of vitamin B12 in your body

Even if the product could be reclassified to make it available for sale in pharmacies, it could not be used more frequently than every 2 3 months, so reclassification to a Pharmacy medicine would not help those who require more frequent injections. and then they also state: Our current advice to private clinics administering vitamin B12 injections which are not licensed medicinal products intravenously for non-medicinal purposes is that we do not regard these to be medicines and that they fall outside of the remit of the MHRA

Frequency and Risk Factors Hypersensitivity reactions to vitamin B12 are rare but may be more likely with long-term or repeated injections, regardless of the chemical form or route of administration