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FTPP removes them permanently

These can include a pins and needles sensation in your hands or feet, balance problems, a swollen tongue, brain fog, and weakness or fatigue

CENTRALLY-ACTING ANTI-OBESITY DRUGS Monoamine Neurotransmitter Modulators With the exception of the glucagon-like peptide 1 (GLP-1) receptor agonist liraglutide, currently available weight loss medications act on the central nervous system to enhance dopamine, norepinephrine, and serotonin action to enhance satiety, diminish hunger, and consequently affect weight loss

No study has tested these three together in animals or humans, so the synergy is reasoned from mechanism, not measured