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Without it, the engine still exists, but it doesnt fire properly

4 Vitamin B3 Vitamin B3, commonly known as niacin, is predominantly found in meats, cereals, dairy products, fish, and eggs, and the recommended daily intake for niacin ranges from 15 mg/day to 20 mg/day for humans ( Niacin is crucial for the biochemistry of the nervous system, playing a significant role in energy metabolism, antioxidant activities, and the synthesis of essential molecules for neuronal function, such as acting in dopamine synthesis ( Nicotinamide adenine dinucleotide (NAD) is a co-substrate for various enzymes, such as sirtuins, polymerases, and cyclic ADP-ribose synthesis ( Niacin also contributes to the synthesis of neurotransmitters, such as serotonin, a derivative of tryptophan, which is pivotal for mood regulation and various neurological functions, such as sleep and appetite, besides impacting cognitive and executive functions (50)

Phospholipase C targets PIP 2 (phosphatidylinositol 4,5-bisphosphate), which is a phospholipid present in the plasma membrane of the cell

Specifically, MSU directly initiates macrophage protein hydrolysis mediated by caspase-1, which processes the NLRP3 inflammasome and heightens the secretion of IL-1 and IL-18 (35)