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Ferroptosis is an iron-dependent programmed cell death mode, which is characterized by excessive Reactive Oxygen Species (ROS) accumulation and lipid peroxidation ( + T cells, Natural Killer (NK) cells and Dendritic cells (DCs) are involved in antitumor immune responses, therefore, ferroptosis of these cells promotes immune evasion ( Moreover, the combination of ferroptosis with immunotherapy and nanomaterials has received substantial attention in recent years

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Zhang L, Wang Z, Lu Z, Shen H, Huang J, Zhao Q, et al

Liver sections in control, CurNPs, NF-CH-CurNPs groups revealed faint reaction while strong reaction was detected in ND (Fig