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Repeated freeze-thaw cycles destroy peptides through ice crystal formation that physically tears apart molecular structures

Neuroscience 26(565):292300 Chakrabarti S, Bisaglia M (2023) Oxidative stress and neuroinflammation in Parkinsons disease: the role of dopamine oxidation products

Introduction Oxidative stress is one of the main causes of the development of different types of diseases, such as cancer [1,2], neurodegenerative pathologies [3,4], liver [5,6], cardiac [7,8], pulmonary [9,10] and renal diseases [11,12]

In particular, glycine helps synthesize bile acid, which is released during the digestive process in order to aid in the breakdown of fats in the small intestine (8)