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Evitar tomar cido alfa lipoico simultneamente con suplementos de hierro utilizados para corregir deficiencia de hierro, espaciando administracin por al menos dos a cuatro horas, dado que cido alfa lipoico particularmente en forma reducida de cido dihidrolipoico puede formar complejos de coordinacin con hierro mediante quelacin donde grupos tiol donan electrones a hierro, y formacin de complejos de hierro-lipoato en tracto gastrointestinal podra reducir absorcin de hierro suplementario desde intestino, comprometiendo efectividad de suplementacin con hierro

(PubMed) Ran L, Zhao W, Tan X, et al

Lipids 34 , 951963 (1999)

PMID: 41697789 Redox Rep ROS-Drp1-mitophagy feedback loop regulates myogenic differentiation via actin cytoskeleton remodeling-mediated MRTF-A/SRF axis