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10.1016/j.schres.2009.03.005 Schizophr

they inhibit the activity of the pro-inflammatory enzyme 5-lipoxygenase and have demonstrated improvements in animal and human models of inflammatory diseases (including asthma, osteoarthritis, and Crohns disease) (Anonymous 2008)

Increased waist circumference, as a manifestation of central obesity, is considered a predictive surrogate of the severity of LUTS in obese patients (69, 70) and animal models of obesity (71)