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Synthesis of (((ethane-1,2-diylbis(azanediyl))bis(carbonyl))bis(4,1-phenylene))diboronic acid(EBPBA) 4-Carboxyphenylboronic acid (3.65 g, 22.00 mmol), ethylenediamine dihydrochloride (1.33 g, 10.00 mmol), HATU (11.40 g, 30.00 mmol) and HOAT (4.08 g, 30.00 mmol) were dissolved in DMF (40 mL) under nitrogen atmosphere and ice bath conditions

This cytidine deaminase enzyme inhibitor enhances decitabine exposure after oral administration

Unfortunately it later turned out that oral bioavailability in humans is dramatically lower than in rodents

doi:10.1053/sonc.2002.35524 Giacomini PG, Napolitano B, Alessandrini M, Di Girolamo S, Magrini A