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Central to this process is the activation of profibrotic cytokines, such as transforming growth factor-beta (TGF-), as well as the activation of fibroblasts and peritubular myoid cells, which secrete abnormal amounts of collagen types I, III, and IV, along with fibronectin (Xiao et al., 2022)

From 1 h pi , the proportion of phagocytosing PBMC also increased significantly, probably due to an increased activity of monocytes as phagocytosing cells