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doi: 10.1039/D1FO01963E 13

Mechanisms of primary and/or acquired resistance include tumor-related factors, such as reduced cell surface expression levels of the target antigen and high levels of complement inhibitors (CD55 and CD59)

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m-TOR Signaling m-TOR Signaling The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin and also referred to as FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase encoded by the MTOR gene in humans