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Candidates for B-12 injections typically include individuals with a vitamin B-12 deficiency, those with certain medical conditions (like pernicious anemia or gastrointestinal disorders), vegetarians or vegans who may not get enough from their diet, or people experiencing fatigue and memory issues potentially linked to low B-12 levels

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"Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice." Scientific Reports