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(3) Regulation of gut microbiota by RIOS Different types of oligosaccharides exert targeted regulation on gut microbiota: Fructooligosaccharides: promote the increased abundance of Bifidobacterium, Lactobacillus, Faecalibacterium, Ruminococcus, Sutterella , and Oscillospira (118)

Increased metabolic rate and ATP consumption trigger mitochondrial dysfunction, consequently leading to reactive oxygen species (ROS) over-production (Tamaki et al., 2014), which is the basis of increased oxidative stress, even in the early stage of CKD

One study identifies miR-125b-5p as a tumor-suppressive microRNA that is significantly downregulated in CRC tissues and cell lines ( In vivo models further validated these findings: suppression of miR-125b-5p promoted CRC lung metastases, whereas RSV treatment effectively hindered this process

Wohl MG, Levy HA, Szutka A, Maldia G