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Further analysis based on genes expressed in skin provided evidence for the existence of intrinsic SSc subsets named inflammatory, fibroproliferative, limited, or normal-like [171]

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Enhancing fusion in pancreatic adenocarcinoma models, either via mitofusin 2 (MFN2) overexpression or DRP1 inhibition, paradoxically increased mitophagy, leading to reduced mitochondrial mass and OXPHOS capacity