glutathione peroxidase and depression Insights into the Role of 3 in Non-Neoplastic Diseases Insights into the Role of

Standard Range: Quest: 373 838 uM The ODX Range: 373 838 uM Low total glutathione is associated with chronic disease, e.g., cancer, genitourinary, GI, cardiovascular, and musculoskeletal diseases (Lang 2000), toxin or drug exposure, oxidative stress, cell damage, immune dysfunction, infections, cardiovascular disease, diabetes, arthritis, malnutrition (Richie 2015), inflammation, cognitive impairment, mental health disorders, mitochondrial dysfunction, cystic fibrosis, liver disease, hypertension, lupus, infertility, HIV, aging, fatigue, B12 deficiency, elevated GGT (Minich 2019), pulmonary fibrosis, neurodegenerative disorders, increased risk of multimorbidity (Perez 2020), vitamin C insufficiency (Waly 2015), acetaminophen toxicity (Kalsi 2011), acute respiratory distress syndrome (ARDS), viral infection, severe COVID-19 (Guloyan 2020), impaired mitochondrial electron transport chain function, uremia, rheumatoid arthritis, myocardial infarction (Teskey 2018), heart failure, cardiac structural abnormalities, and increased severity of ventricular dysfunction (Damy 2009)

PMC 2143612

The Institute of Medicine has not established a tolerable upper intake level of B12 because studies show no adverse health effects when taking excess levels of B12, either through food or supplements

European Journal of Pharmaceutics and Biopharmaceutics, 86 (2), 251259