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Description

- Injection Sites: Subcutaneous injections are typically administered into fatty tissue (e.g., abdomen)

It may lead to muscle breakdown or joint pain

We examined liver function as well as survival of mice after specific knockdown of HK2 in hepatocytes ( Hk2 f/f

In addition, kidney weight was markedly reduced in GH-treated and untreated JAK2 -/- mice compared to controls, indicating the importance of circulating IGF-1 in kidney growth, whereas locally produced IGF-1 seems not to have a significant impact on kidney growth