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The primary functions of FC and acylcarnitines (AC), mainly acetyl-L-carnitine (ALC) in humans, are the transport of long-chain fatty acids (FAs) to the mitochondrial matrix and maintaining the mitochondrial homeostasis of coenzyme A (CoA) during mitochondrial oxidation of these acids [49]

3 VEGF inhibitors and cancer Clinically, two main classes of VEGF-pathway inhibitors are in widespread use