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Where early interventions focused on systemic metabolic stimulationoften accompanied by widespread adrenergic side effectscontemporary research focuses on tissue-specific targeting

Sources The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis Journal of Personalized Medicine (2021) Vit B12 supplement of 500 g/d for eight weeks does not normalize urinary methyl-malonic acid or other biomarkers of vitamin B12 status in elderly people J Nutr