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It has been demonstrated that the involvement of oxidative stress and inflammation are associated with the pathogenesis of CVD

DOI: 10.1586/17512433.2013.841078 Kittayaruksakul, S., Zhao, W., Xu, M., Ren, S., Lu, J., Wang, J., Downes, M., Evans, R.M., Venkataramanan, R., Chatsudthipong, V., Xie, W

The nNOS is expressed primarily in specific neurons within the central nervous system (CNS) and was the first NOS isoform identified in 1982 in neuroblastoma cells [21]