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Nature (2002) 418:1915.10.1038/nature00858 36 DumitriuIEBaruahPValentinisBVollREHerrmannMNawrothPPet alRelease of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products

The 5HT 2C receptors are suspected in control of food intake as mice lacking this gene become obese from increased food intake and are also subject to fatal seizures

For instance, MMP-3 promotes EMT by activating Wnt/-catenin and TGF- signaling pathways, while simultaneously inducing fibroblast proliferation and collagen deposition, as demonstrated by reduced fibrosis in MMP-3-knockout mice following bleomycin challenge (Pardo et al., 2016