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June 2024

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It suggests that the neuroprotective effect of miR-125b inhibition can be due to both downregulation of proinflammatory mediators and the stimulation of M2-activator parameters, such as BDNF in ALS [81]

It was suggested that the strong anti-neuroinflammatory activity of the fresh ginger extract was largely contributed by 10-gingerol ( In addition, 6-, 8- and 10-gingerols/shogaols were shown to inhibit the canonical (NOD)-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome-mediated IL-1 secretion in ATP- and LPS-stimulated THP-1 macrophages