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3 Rare But Serious Side Effects of Vitamin B12 Supplements Constipation in B12 deficiency is primarily neurogenic, due to autonomic and enteric neuropathy causing slow gut motility Constipation may precede anemia Often improves after B12 replacement Think of B12 Does Vitamin B12 Cause Constipation? UK Medical Facts Bolt Pharmacy Vitamin B12 Deficiency: Causes, Symptoms, and Treatment
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