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These particles can encapsulate hydrophilic, hydrophobic, and amphiphilic drugs simultaneously

Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrn M, Chen T, Marcinek DJ, Dorn GW 2nd, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS (2011) Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure

Afterward, corresponding HRP-conjugated goat anti-rabbit/mouse secondary antibodies (1:100) were introduced and incubated for 30 min at 37 C

In general, the acceptability of a risk of an unwanted effect is related to the severity of the disease being treated