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Moreover, preconditioning MSC-EVs with traditional Chinese medicine (TCM) components, such as those from Salvia miltiorrhiza, upregulates hsa-miR-27a-5p_R-1 to modulate the signal transducer and activator of transcription 3 (STAT3)-SHANK2 (SH3 and multiple ankyrin repeat domains protein 2) axis, significantly improving the EVs anti-fibrotic and tissue-repair capabilities [194]

Die Therapie fhrte zu: Rckgang des PSA-Werts Rckbildung von Metastasen im PSMA-PET Verlngerung des progressionsfreien berlebens Es traten keine Hinweise auf systemischen Thiaminmangel oder andere relevante Nebenwirkungen auf