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(117) observed that resveratrol restores TZP formation and function in PCOS models by enhancing calcium ion (Ca + )/calmodulin (CaM) transmembrane transport to the cytoplasm

10.1038/s41598-021-81268-7 192 ShiY.ChenJ.QuD.SunQ.YuY.ZhangH.et al (2024)

also found that blocking IFNAR could rescue this effect of manganese

Future research should prioritize the systematic validation of the synergistic therapeutic effects of the above drugs through this signaling axis in OA animal models