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Hodge S, Matthews G, Mukaro V, et al

Adiponectin, a polypeptide synthesised and released by adipocytes in relatively high quantities, is characterised by potent anti-inflammatory, antidiabetic, antiatherogenic and insulin-sensitising properties

Subsequently, AngI is cleaved via ACE to angiotensin II (AngII)

Within cellular contexts, autophagy can function as a protective compensatory mechanism in response to elevated iron levels, thereby mitigating cell death associated with oxidative stress and other detrimental factors [115]