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Another dosing recommendation begins with 1000 mcg daily for the first seven to 10 days, then 1000 mcg weekly for a month, followed by 1000 mcg monthly for life

Moderate exercise maintains ROS at normal physiological levels, where ROS act as key signaling molecules to activate the Nrf2 pathway and upregulate the expression of endogenous antioxidants such as HO-1, SOD, and GPx (Merry and Ristow, 2016)

Nat Prod Commun 9(4):1934578X1400900434 Pasupuleti VR, Sammugam L, Ramesh N, Gan SH (2017) Honey, propolis, and royal jelly: a comprehensive review of their biological actions and health benefits