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doi: 10.1186/1750-9378-9-38 160 WongYMeehanMTBurrowsSRDoolanDLMilesJJ

Some individuals may observe changes within a few weeks, while others might require longer treatment periods

Metal chelating agents ethylenediaminetetraacetic acid (EDTA) and ethylene glycol tetraacetic acid (EGTA) exhibit moderate inhibition, suggesting contribution of a metal ion in the active conformation of enzyme