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doi: 10.1038/s41591-018-0308-z 242 Mirsepasi-LauridsenHCVallanceBAKrogfeltKAPetersenAM

Keep in mind that the research around MTHFR is still evolving

Methods: Gene expression was analyzed using RNA sequencing (RNA-seq), single-cell RNA sequencing (scRNA-seq), and 10x spatial transcriptomics in primary human hepatic stellate cells (hHSCs) and a CCl4-liver fibrosis induced murine model