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The PPP has been identified as a mechanism for protecting neurons from oxidative stress (Bolanos and Almeida, 2010)

Incubations were terminated by addition of ice-cold perchloric acid at a final concentration of 1% and plates were kept on ice for 10 min

Through ATF4-mediated integrated stress responses, cancer cells acquire not only drug persistence, ferroptosis sensitivity, and also metastatic phenotype 45,46,47