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Our liver also processes and repackages fats

For example, shikonins anti-tumor effect in GC is closely linked to its ferroptosis-inducing activity, and in this process, the DLEU1/mTOR/GPX4 pathway plays a crucial role, as revealed by Wang et al

Guo et al., 2004)

386,387 The mitophagy activator urolithin A, which indirectly inhibits mTOR through the PI3K/AKT/mTOR pathway, has been shown to reduce cytosolic mtDNA-dependent activation of the cGAS/STING pathway and subsequent inflammation