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Bloem, B

2.2 Mitochondrial dysfunction and oxidative stress Mitochondrial complex I deficiency is consistently observed in PD, leading to impaired ATP synthesis and overproduction of reactive oxygen species (ROS) (Chang and Chen, 2020

Materials and methods Study design and participants This single-center, prospective, case-control study was conducted between May 1, 2024, and September 1, 2024, at the Rheumatology Outpatient Clinic of Recep Tayyip Erdoan University Training and Research Hospital