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This suggests that the ND6 mutation and not the MT-CYB mutation is involved in the LS pathology in this patient

PMID: 34502195 Biomolecules(20S)G-Rh2 Inhibits NF-B Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2

Particularly among the elderly, those with untreated hearing loss are less likely to participate in social activities and more likely to report levels of depression and anxiety (Bess et al., 2009)