igf-1 lr3 and mk677 The role of IGF/IGF-1R signaling in the regulation of cancer stem cells | Clinical Translational Oncology IGF-1R inhibition induces MEK phosphorylation

This had a dramatic effect on reducing mortality from infections

The seed has a very complex chemical composition (it contains both fixed and volatile oil) and is used traditionally for a bunch of "anti-something" abilities including antitumor, antidiabetic, antihistaminic, anti-inflammatory, and antimicrobial properties

Al Ofair AA, Alamri M, Alshehri SH, Alzahrani ZA, Alrumaih AK, Syed W, AlArifi MN, Assiri MA, Muayqil TA, Alwhaibi A

Furthermore, one article suggests that it suppresses caspase-dependent apoptosis (decreases caspase activity responsible for programmed cell death) that increases during the process of aging [10]