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Meanwhile, we investigated the role of ER stress during the vitamin B 12 treatment for TBI by inspecting changes in neuronal apoptosis, microtubule, myelin regeneration, and axonal growth

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B12 plays a key role in: Red blood cell production DNA synthesis Nervous system function Cellular energy metabolism B12 supplementation is commonly recommended for individuals with confirmed deficiency or absorption concerns

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(2004, Annals of the New York Academy of Sciences) showed that T4 and its derived fragments greatly upregulate VEGF (vascular endothelial growth factor) expression in endothelial cells, promote endothelial tube formation in Matrigel assays, and reduce ischemic tissue loss in cardiac injury models

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