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Bone marrow stromal cell-derived exosomal circular RNA improves diabetic foot ulcer wound healing by activating the nuclear factor erythroid 2-related factor 2 pathway and inhibiting ferroptosis

This selective form of autophagy releases stored iron, which can then be utilised in biosynthetic pathways

In lung cancer cells, SHMT1 knockdown induces cell cycle arrest, leading to p53-dependent apoptosis

This dichotomy may arise from several factors: i) TXNIP-mediated regulation of autophagy is context-dependent, varying across different disease settings (163)