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Studies show constipation rates below 5% with NAC supplementation at standard doses (6001800mg daily)

In this specific cycle: 1 Hydrogen peroxide, a free radical and reactive oxygen species, is converted into water (harmless), and oxygen 2 Two molecules of reduced Glutathione [GSH (the active antioxidant form of glutathione)] are used by the Glutathione peroxidase enzyme to neutralize one molecule of hydrogen peroxide 3 NADPH is used by glutathione reductase enzyme to reduce ("recycle") glutathione disulfide back into usable reduced glutathione Key players: Selenium: Essential for the enzyme that initiates the breakdown of hydrogen peroxide Riboflavin (FAD - coenzyme form of riboflavin): essential for the enzyme that restores the oxidized Glutathione back to its more useful state

Mice were bred and maintained at the Lockey preclinical research facility of the Weizmann Institute of Science

This feature makes them highly reactive