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J Neurochem 92:283293 Toppo S, Floh L, Ursini F, Vanin S, Maiorino M (2009) Catalytic mechanisms and specificities of glutathione peroxidases: Variations of a basic scheme

doi: 10.21608/svu.2021.55868.1092

Therefore, melatonin is believed to reduce the status of CIPN by limiting the development of mechanical hypersensitivity and altering peripheral nerve function

Nuclear factor erythroid-2 counteracts oxidative reactions by regulating related factors, such as nuclear factor erythroid-2-related factor-2 (Nrf2), reducing cellular oxidative damage