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[DOI] [PubMed] [Google Scholar] 66.Falamarzi K, Malekpour M, Tafti MF, Azarpira N, Behboodi M, Zarei M

Substitution of valine with norleucine in the first position enhanced activity [85]

J Peripher Nerv Syst

It replenishes mitochondrial energy in neurons and re-regulates the circadian clock (via SIRT1/CLOCK), normalizing dopamine synthesis in the nucleus accumbens to reduce cravings and withdrawal anxiety